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Rotavirus and adenovirus prevalence at Tepecik education and research hospital (Turkey)

Gulfem Ece1, Pinar Samlioglu, Temel Ulker

  • 1Tepecik Education and Research Hospital Department of Infectious Diseases and Clinical Microbiology, Izmir, Turkey.

Le Infezioni in Medicina
|July 7, 2012
PubMed

Insights

Rotavirus was the most common cause of viral gastroenteritis in children, detected in 18.07% of stool samples. Adenovirus was found in 1.2%, highlighting the importance of viral diagnosis to prevent unnecessary antibiotic use.

Area of Science:

  • Medical Microbiology
  • Virology
  • Pediatric Gastroenterology

Background:

  • Diarrhoea is a global health concern, particularly in children.
  • Rotaviruses and enteric adenoviruses (types 40 and 41) are leading viral causes of childhood gastroenteritis.
  • Accurate etiological diagnosis is crucial for effective management and to prevent antibiotic misuse.

Purpose of the Study:

  • To determine the prevalence of rotavirus and adenovirus in fecal samples from pediatric patients.
  • To assess the role of these viruses as causative agents of gastroenteritis in the study population.
  • To emphasize the diagnostic significance of viral antigen detection in stool specimens.

Main Methods:

  • A total of 1112 stool samples were collected from May 2008 to May 2010.
  • Samples were screened for rotavirus and adenovirus antigens using a commercially available immunochromatographic EIA kit (Rotavirus/Adenovirus Combo Rapid Test Device).
  • Data analysis focused on the prevalence rates of detected viral antigens.

Main Results:

  • Rotavirus antigen was detected in 201 samples (18.07%).
  • Adenovirus antigen was detected in 14 samples (1.2%).
  • Rotavirus was identified as the predominant viral agent responsible for gastroenteritis in this cohort.

Conclusions:

  • Rotavirus is a significant cause of viral gastroenteritis in children within the studied population.
  • Early detection of viral pathogens like rotavirus and adenovirus aids in appropriate clinical management.
  • Implementing viral diagnostic testing can reduce the unnecessary prescription of antibiotics for gastroenteritis.

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