Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Computer-controlled dynamic phantom for ultrasound hyperthermia studies.

J Zaerr1, R B Roemer, K Hynynen

  • 1Department of Radiation Oncology, University of Arizona, Tucson 85721.

IEEE Transactions on Bio-Medical Engineering
|November 1, 1990
PubMed
Summary

A novel dynamic phantom system using canine kidneys and computer-controlled perfusion was developed to evaluate hyperthermia equipment. This system allows flexible spatial and temporal flow patterns for realistic testing.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Focused ultrasound delivery of a selective TrkA agonist rescues cholinergic function in a mouse model of Alzheimer's disease.

Science advances·2020
Same author

Ultrasound-responsive droplets for therapy: A review.

Journal of controlled release : official journal of the Controlled Release Society·2018
Same author

Gene delivery to the spinal cord using MRI-guided focused ultrasound.

Gene therapy·2015
Same author

The targeting accuracy of a preclinical MRI-guided focused ultrasound system.

Medical physics·2015
Same author

Modeling the pattern of contrast extravasation in acute intracerebral hemorrhage using dynamic contrast-enhanced MR.

Neurocritical care·2014
Same author

An in vivo, MRI-integrated real-time model of active contrast extravasation in acute intracerebral hemorrhage.

AJNR. American journal of neuroradiology·2014

Area of Science:

  • Biomedical Engineering
  • Medical Physics
  • Thermal Medicine

Background:

  • Evaluating hyperthermia heating equipment requires realistic phantoms.
  • Existing phantoms may lack dynamic physiological simulation capabilities.

Purpose of the Study:

  • To design, construct, and test a dynamic phantom system for hyperthermia equipment evaluation.
  • To enable flexible simulation of physiological responses during hyperthermia treatment.

Main Methods:

  • Developed a system with four in vitro preserved canine kidneys.
  • Utilized a single pump, computer-controlled valves, and flow meters for perfusion.
  • Implemented computer control for spatial and temporal flow pattern flexibility.

Main Results:

Related Experiment Videos

  • Demonstrated capability for step and ramp changes in flow rates.
  • Successfully simulated temperature-dependent flow to mimic physiological responses.
  • The system provides a flexible platform for hyperthermia equipment testing.

Conclusions:

  • The dynamic phantom system offers a versatile tool for hyperthermia equipment evaluation.
  • Computer-controlled perfusion allows for realistic simulation of thermal physiology.
  • This system enhances the assessment of hyperthermia treatment efficacy and safety.