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Published on: February 28, 2012
Supporting Treatment decision making to Optimise the Prevention of STROKE in Atrial Fibrillation: the STOP STROKE in
Melina Gattellari1, John M Worthington, Dominic Y Leung
1Ingham Institute, Liverpool, Australia.
Insights
This study tested a distance education program to increase anticoagulation use for stroke prevention in atrial fibrillation (AF) patients. The intervention aims to reduce strokes by improving guideline-adherent prescribing in primary care.
Area of Science:
- Cardiovascular Medicine
- Public Health
- Clinical Trials
Background:
- Suboptimal anticoagulation uptake for stroke prevention in atrial fibrillation (AF) remains a persistent challenge for over two decades.
- Despite strong evidence, effective treatments are underutilized, leading to preventable strokes.
Purpose of the Study:
- To evaluate a distance education intervention designed to improve oral anticoagulation uptake in primary care for patients with atrial fibrillation.
- To assess the effectiveness of augmenting academic detailing with expert feedback in enhancing anticoagulation prescribing.
Main Methods:
- A national, cluster-randomised controlled trial (STOP STROKE in AF study) involving Australian general practitioners.
- Intervention includes mailed educational materials, telephone-based peer academic detailing, and randomized specialist feedback timing (pre- or post-audit).
- Primary outcome: proportion of AF patients receiving oral anticoagulation at three-month posttest audit.
Main Results:
- The study is designed to measure the impact of the intervention on anticoagulation prescribing rates.
- Data collection focuses on the primary outcome: the proportion of patients with atrial fibrillation receiving oral anticoagulation.
- Secondary analyses will assess the effectiveness of the augmented academic detailing approach.
Conclusions:
- The STOP STROKE in AF study evaluates a feasible distance education intervention to prevent strokes in atrial fibrillation patients.
- The trial systematically tests the benefit of expert feedback combined with academic detailing for improving anticoagulation management.
Background:
Suboptimal uptake of anticoagulation for stroke prevention in atrial fibrillation has persisted for over 20 years, despite high-level evidence demonstrating its effectiveness in reducing the risk of fatal and disabling stroke.
Methods:
The STOP STROKE in AF study is a national, cluster randomised controlled trial designed to improve the uptake of anticoagulation in primary care. General practitioners from around Australia enrolling in this 'distance education' program are mailed written educational materials, followed by an academic detailing session delivered via telephone by a medical peer, during which participants discuss patient de-identified cases. General practitioners are then randomised to receive written specialist feedback about the patient de-identified cases either before or after completing a three-month posttest audit. Specialist feedback is designed to provide participants with support and confidence to prescribe anticoagulation. The primary outcome is the proportion of patients with atrial fibrillation receiving oral anticoagulation at the time of the posttest audit.
Discussion:
The STOP STROKE in AF study aims to evaluate a feasible intervention via distance education to prevent avoidable stroke due to atrial fibrillation. It provides a systematic test of augmenting academic detailing with expert feedback about patient management.
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