Related Experiment Video
Updated: May 20, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
[French-Brazilian school of nephrology]
Rodrigo Bueno de Oliveira1, Jenner Cruz, Tilman Bernhard Drüeke
1Université de São Paulo (USP), division de néphrologie, São Paulo, Brésil.
This article highlights the enduring collaboration between French and Brazilian medicine, particularly in nephrology, over the last 60 years. It celebrates the scientific output and training of new specialists resulting from this partnership.
Area of Science:
- Nephrology
- Medical History
- International Medical Collaboration
Background:
- The historical relationship between French and Brazilian medicine dates back to the early 19th century.
- Specific collaborations in nephrology began in the mid-20th century, fostering a distinct Franco-Brazilian school.
- This partnership has spanned over six decades, significantly impacting medical research and education.
Observation:
- The Franco-Brazilian nephrology school has produced over a thousand scientific publications.
- More than two hundred medical professionals have been trained as disciples within this collaborative framework.
- Training involved Brazilian nephrologists completing studies in France, subsequently educating new generations in Brazil.
Findings:
- The sustained exchange has led to a substantial body of scientific work in nephrology.
- A significant number of specialists have been educated through this Franco-Brazilian medical network.
- The collaboration has established a strong legacy in the field of kidney disease research and treatment.
Implications:
- This enduring scientific and educational exchange strengthens international medical research capabilities.
- The training model has created a robust network of nephrologists in Brazil, influenced by French medical expertise.
- The article serves as a historical record and commemoration of this fruitful medical partnership.
Related Concept Videos
Physiology of the Genitourinary System I: Renal Blood Flow and Glomerular Filtration
Chronic Kidney Disease III: Interprofessional Care
Renal Drug Excretion: Glomerular Filtration
Drugs gain access to the kidney via the renal artery, which progressively branches off into afferent arterioles.
Renal Regulation of Acid-Base Balance
In the kidneys, cells within the proximal convoluted tubules (PCT) and the collecting ducts secrete hydrogen ions (H+) into the tubular fluid. Specifically, in the PCT, Na+/H+ antiporters secrete H+ while reabsorbing Na+.
However, the intercalated cells in...
Drug Dosing in Renal Diseases: Measurement of Glomerular Filtration Rate
Renal Drug Excretion: Tubular Secretion

