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Updated: May 20, 2026
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Published on: August 9, 2024
Management and recurrence of keratocystic odontogenic tumor: a systematic review
Nigel R Johnson1, Martin D Batstone, Neil W Savage
1Principal Researcher, Maxillofacial Department, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
Objectives:
The objective of this study was to evaluate the most up-to-date treatment modalities and respective recurrence rates for keratocystic odontogenic tumor (KCOT).
Study Design:
A systematic review of the literature from 1999 to 2010 was undertaken examining treatment and recurrence rates for KCOT. Four inclusion criteria were defined for articles to then be analyzed against 8 standards.
Results:
Of the 2736 published articles, 8 met the inclusion criteria. When merging the data, enucleation and enucleation with adjunctive measures (other than Carnoy's solution) had recurrence rates of 25.6% and 30.3%, respectively. Marsupialization with adjunctive measures produced a recurrence rate of 15.8%, whereas enucleation with Carnoy's solution presented a recurrence rate of 7.9%. Only one resection case had recurrence (6.3%).
Conclusions:
The enucleation technique with the use of adjunctive procedures (other than Carnoy's solution) provides a higher recurrence rate than any other treatment modality.
