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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...

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Related Experiment Video

Updated: May 20, 2026

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization
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Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Published on: November 17, 2023

Update on prostate pathology.

Adeboye O Osunkoya1

  • 1Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA. adeboye.osunkoya@emory.edu

Pathology
|July 10, 2012
PubMed
Summary
This summary is machine-generated.

This review updates prostate pathology, covering the Gleason grading system, radical prostatectomy specimen handling, adenocarcinoma variants, treatment effects, and prostate cancer biomarkers.

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Last Updated: May 20, 2026

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Area of Science:

  • Urological Pathology
  • Oncology

Background:

  • The International Society of Urological Pathologists (ISUP) celebrates its 20th anniversary.
  • Significant advancements in prostate pathology have occurred over the past two decades.

Purpose of the Study:

  • To provide a timely update on key developments in prostate pathology.
  • To highlight contributions of ISUP members to the field.

Main Methods:

  • Historical perspective on prostate pathology.
  • Review of recent advances and current practices.

Main Results:

  • Discussion of the Gleason grading system.
  • Update on handling and staging of radical prostatectomy specimens.
  • Exploration of prostatic adenocarcinoma variants.
  • Analysis of treatment effects on prostate tissue.
  • Overview of other tumors involving the prostate.
  • Review of prostate cancer biomarkers.

Conclusions:

  • The past two decades have seen substantial progress in understanding and diagnosing prostate pathology.
  • Continued research and collaboration are essential for further advancements in urological pathology.