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Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
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Role of Vitamins in Maintaining Bone Health

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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
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[Vitamin D metabolism].

U Lange1

  • 1Kerkhoff-Klinik, Professur für Rheumatologie, Osteologie, Physikalische Medizin, Universität Gießen, Benekestr. 8, 61231, Bad Nauheim, Deutschland. u.lange@kerckhoff-klinik.de

Zeitschrift Fur Rheumatologie
|July 10, 2012
PubMed
Summary
This summary is machine-generated.

This review covers vitamin D metabolism, its functions, and its role in inflammatory rheumatic diseases. It also provides guidance on vitamin D supplementation, including safety and practical advice for healthcare professionals.

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Area of Science:

  • Endocrinology and Metabolism
  • Rheumatology

Context:

  • Vitamin D plays a crucial role in calcium homeostasis and bone health.
  • Emerging evidence suggests a link between vitamin D deficiency and inflammatory rheumatic diseases.
  • Understanding vitamin D's impact is vital for managing these conditions.

Purpose:

  • To review the current understanding of vitamin D metabolism and function.
  • To explore the association between vitamin D and inflammatory rheumatic diseases.
  • To offer evidence-based recommendations for vitamin D supplementation in clinical practice.

Summary:

  • This review synthesizes current knowledge on vitamin D's metabolic pathways and physiological roles.
  • It examines the intricate relationship between vitamin D status and the pathogenesis and progression of inflammatory rheumatic diseases.
  • The article provides practical insights into safe and effective vitamin D supplementation strategies.

Impact:

  • Enhances understanding of vitamin D's multifaceted roles in health and disease.
  • Informs clinical decision-making for patients with inflammatory rheumatic conditions.
  • Provides actionable guidance for optimizing vitamin D therapy and patient outcomes.