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[Magnetic resonance angiography in rheumatology]
T A Bley1, B Ostendorf, A Scherer
1Klinik und Poliklinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Hamburg - Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland. t.bley@uke.de
Zeitschrift Fur Rheumatologie
|July 10, 2012
Summary
Magnetic resonance imaging (MRI) and angiography (MRA) show promise for diagnosing large vessel vasculitis by visualizing artery walls and inflammation. These techniques can guide biopsies and monitor treatment, offering an alternative to invasive angiography for central nervous system vasculitis.
Area of Science:
- Radiology
- Vascular Imaging
- Inflammatory Diseases
Context:
- Large vessel vasculitis diagnosis presents challenges.
- Non-invasive imaging is crucial for patient management.
- Established diagnostic methods have limitations.
Purpose:
- To review the potential and limitations of MRI and MRA in diagnosing large vessel vasculitis.
- To highlight the role of MRI and MRA in visualizing vascular inflammation and guiding biopsies.
- To assess MRA as an alternative to catheter angiography for CNS vasculitis.
Summary:
- MRI and MRA visualize lumen and vessel walls of large/medium arteries, detecting mural inflammatory changes via contrast uptake.
- Combined cranial MRI and thoracic aorta MRA assess cranial, intracranial, and extracranial involvement.
- Specific MRI/MRA protocols (3T, monophasic, time-resolved) are detailed for diagnostic accuracy.
Impact:
- MRI/MRA can identify optimal segments for temporal artery biopsy and monitor treatment response.
- These techniques offer a non-invasive alternative to catheter angiography for CNS vasculitis evaluation.
- Expected multicenter study results will further define diagnostic accuracy of these advanced imaging methods.
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