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Published on: July 24, 2016
Intracranial calcifications, microcephaly, and seizure. If not congenital infection, what could it be?
Wafaa Eyaid1, Ruqaiah S Al-Tassan, Doha M Al-Nouri
1Department of Pediatrics, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia. eyaidw@ngha.med.sa
Abstract:
Intracranial calcification has a variety of etiologies; among those are environmental and metabolic disturbances involving calcium homeostasis. The main environmental factors resulting in intracranial calcification are congenital infections with toxoplasmosis, and cytomegalovirus. There are increasing reports on cases showing pictures of congenital infection in the absence of confirmative positive TORCH screen, and there are many cases reported worldwide sharing the same presentation labeled as autosomal recessive congenital infection-like syndrome or pseudo-TORCH syndrome (OMIM 600158).
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