Influence of different anesthesia on liver and renal function in elderly patients undergoing laparoscopic colon or...

To investigate the influence of different anesthesia methods on liver and renal function in elderly patients undergoing laparoscopic colon or rectal resection.

Forty ASA I-II elderly patients undergoing elective laparoscopic colon or rectal resection were randomly divided into 2 groups (n=20 each): Group A: routine general anesthesia and Group B: general combined epidural anesthesia. All patients received general anesthesia, tracheal catheterized and mechanical ventilation. Data of liver and renal function were noted at these time points: before operation (T1), during operation (T2), 1-day after operation (T3), 2-day after operation during bowel anastomoses (T4), 3-day after operation (T5). Duration of surgery, blood loss, urine output and intravenous fluid volume was registered.

Compared with group A, the total fluid volume and urine volume were increased in group B (p<0.05), while the amount of fentanyl was decreased (p<0.05). TP, TBIL and DBIL between the two groups were not significantly different (p>0.05). Compared with group A, group B ALT/BUN decreased at T2 and T3, AST decreased at T2, Cr at T3 decreased, ALB decreased at T2 (p<0.05).

Continuous epidural block compound general anesthesia in elderly laparoscopic colorectal resection surgery is more conducive to the protection of perioperative liver and kidney function.