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Frequency and predictors of renal artery stenosis in hypertensive patients undergoing coronary angiography

Hikmet Yorgun1, Giray Kabakçı, Uğur Canpolat

  • 1Develi State Hospital, Kayseri, Turkey.

Angiology
|July 10, 2012
PubMed

Insights

Renal artery stenosis (RAS) is common in hypertensive patients undergoing heart procedures. Key predictors include age, hypertension duration, kidney function, and coronary artery disease severity, highlighting the need for RAS screening.

Area of Science:

  • Cardiology
  • Nephrology
  • Vascular Medicine

Background:

  • Renal artery stenosis (RAS) and coronary artery disease (CAD) share common risk factors.
  • Hypertension is a prevalent condition often coexisting with cardiovascular and renal pathologies.
  • Identifying RAS in patients with CAD is crucial for prognosis and management.

Purpose of the Study:

  • To determine the frequency of RAS in hypertensive patients undergoing elective coronary angiography.
  • To identify independent predictors of RAS in this patient cohort.
  • To assess the relationship between RAS severity and coronary artery disease burden.

Main Methods:

  • Prospective investigation of 832 hypertensive patients undergoing simultaneous coronary and renal angiography.
  • Classification of RAS into mild, moderate, and severe categories.
  • Statistical analysis to identify independent predictors of RAS, including demographic, clinical, and angiographic variables.

Main Results:

  • The prevalence of significant (≥50%) RAS was 16.3% among the study population.
  • Age, duration of hypertension, estimated glomerular filtration rate, Gensini score, and multivessel disease were identified as independent predictors of RAS.
  • A stepwise increase in the Gensini score was observed with increasing severity of RAS.

Conclusions:

  • Hypertensive patients undergoing coronary angiography have a significant prevalence of RAS.
  • Specific risk factors predict the presence of RAS, warranting targeted investigation.
  • Early detection and management of RAS in this population may improve patient outcomes.

Keywords:
coronary artery diseasehypertensionrenal artery stenosis

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