Biochemical differences in ethnic groups in Durango, Mexico

Area of Science:

• Biochemistry
• Anthropology
• Public Health

Background:

• Indigenous populations and distinct ethnic groups often exhibit unique physiological characteristics.
• Understanding these differences is crucial for targeted health interventions and research.

Purpose of the Study:

• To evaluate biochemical variations among Tepehuano indigenous, Mennonite, and Mestizo populations in Durango, Mexico.
• To identify potential correlations between biochemical markers and demographic factors.

Main Methods:

• A cohort of 334 volunteers (Mennonite, Mestizo, Tepehuano indigenous) aged 15-80 years was studied.
• Clinical history and rapid assays for aspartate aminotransferase (AST), alanine aminotransferase (ALT), uric acid, urea, and creatinine were performed.

Main Results:

• Significant differences in age, weight, and height were observed across the groups, with higher values in males.
• Plasma urea levels were highest in Mennonites, followed by Mestizos, then Tepehuano indigenous people.
• Abnormal levels of AST, ALT, and uric acid were more prevalent in Tepehuano indigenous individuals, while urea and creatinine were higher in Mestizos.

Conclusions:

• Biochemical test results varied significantly among the studied populations.
• Lifestyle factors, including diet and sanitary habits, are proposed as explanations for the observed biochemical differences.