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Related Experiment Videos

[A new approach to tuberculosis case management].

T Mori1

  • 1Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose.

Kekkaku : [Tuberculosis]
|November 1, 1990
PubMed
Summary
This summary is machine-generated.

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Schedule-dependent inhibition of thymidylate synthase by 5-fluorouracil in gastric cancer.

Cancer·1992
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Heterophile antigens in serous cystadenocarcinoma of the human ovary.

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Evaluation of an improved dot-immunobinding assay for carcinoembryonic antigen determination in nipple discharge in early breast cancer: results of a multicenter study.

Japanese journal of clinical oncology·1992
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The effect of DHAS on steroidogenesis of the human corpus luteum.

Endocrinologia japonica·1992
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The characteristics of interval breast cancer in mass screening.

The Tokushima journal of experimental medicine·1992
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[The relationship between evaluation of school stressors and stress responses in junior high school students].

Shinrigaku kenkyu : The Japanese journal of psychology·1992

Japan

Area of Science:

  • Public Health
  • Epidemiology
  • Infectious Diseases

Context:

  • Recent tuberculosis (TB) epidemiology in Japan shows concerning trends.
  • A plateau in the incidence of bacteriologically confirmed TB cases.
  • An increasing incidence of smear-positive TB cases among the elderly population.

Purpose:

  • To analyze recent trends in Japan's tuberculosis epidemiology.
  • To investigate the reasons behind the slowing decrease in TB incidence.
  • To assess the future prospects of TB elimination in Japan.

Summary:

  • The decreasing trend of tuberculosis incidence in Japan has slowed, with bacteriologically confirmed cases remaining constant and smear-positive cases rising in older adults.
  • These epidemiological shifts, coupled with a significant generation gap in TB infection prevalence, threaten Japan's goal of TB elimination.

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  • Current chemoprophylaxis coverage is low (estimated 15%), highlighting the need for enhanced contact tracing and examination strategies.

    • Impact:

    • The findings suggest that current TB control strategies may be insufficient to achieve elimination.
    • Future TB microepidemics are a growing concern due to generational differences in infection prevalence.
    • Increased emphasis on contact examination is crucial for future TB control efforts in Japan.