Related Experiment Video
Updated: May 20, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Common mental disorders and long-term sickness absence in a general working population. The Hordaland Health Study
A K Knudsen1, S B Harvey, A Mykletun
1Department of Health Promotion and Development, Faculty of Psychology, University of Bergen, Norway. ann.knudsen@psych.uib.no
Objective:
To examine and compare the prospective effect of the common mental disorders (CMD) anxiety and depression on duration and recurrence of sickness absence (SA), and to investigate whether the effect of CMD on SA is detectable over time.
Method:
Information from a large epidemiological health study (N = 13 436) was linked with official records of SA episodes lasting ≥16 days up to 6 years after participation. Common mental disorders were assessed with the Hospital Anxiety and Depression Scale (HADS). Associations were analysed with Cox regression and multinomial logistic regression models controlling for potential covariates.
Results:
Comorbid anxiety and depression, and anxiety only were significant risk factors for SA after adjusting for covariates, whilst depression only was not. Anxiety and depression were stronger predictors for longer duration of SA episodes compared with shorter duration and associated with more frequent recurrence of SA. There was a general trend toward the effect of CMD on SA becoming weaker over time; however, the effect of anxiety only on SA remained stable throughout the follow-up.
Conclusion:
Common mental disorders are long-lasting predictors of onset, duration and recurrence of SA. Anxiety appears to be a more important contributor to long-term SA than previously described in the literature.
Related Concept Videos
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Depressive Disorders: MDD and Dysthymia
Factors Affecting Illness
For instance, risk factors are connected to illness, disability,...
Classification of Illness
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...
Models of Health Promotion and Illness Prevention II
The agent-host-environment model states that disease results from...
Dimensions of Health and Illness