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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
Sex Linked Disorders01:43

Sex Linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Sex-linked Disorders01:43

Sex-linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.

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Related Experiment Video

Updated: May 20, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Challenges in sexual medicine.

Selim Cellek1, Annamaria Giraldi

  • 1Cranfield Health, Cranfield University, Bedfordshire MK43 0AL, UK. s.cellek@cranfield.ac.uk

Nature Reviews. Urology
|July 11, 2012
PubMed
Summary

Sexual medicine research faces funding challenges and slowed progress due to successful erectile dysfunction treatments. However, unmet needs in premature ejaculation, severe ED, and hypoactive sexual desire disorder will drive future therapeutic development.

Area of Science:

  • Sexual medicine
  • Biomedical research

Background:

  • The field of sexual medicine has experienced significant advancements but is currently facing momentum loss.
  • Economic downturns have led to reduced research funding and lower prioritization by regulatory bodies and pharmaceutical companies.
  • The success of phosphodiesterase type 5 (PDE5) inhibitors for erectile dysfunction (ED) has inadvertently slowed research in this specific area.

Approach:

  • Despite challenges, ongoing research is crucial for addressing unmet medical needs.
  • Focus remains on developing novel therapeutic approaches for various sexual dysfunctions.
  • Continued investigation aims to improve patient outcomes and quality of life.

Key Points:

  • Erectile dysfunction (ED) treatments have seen success, but significant unmet needs persist.

Related Experiment Videos

Last Updated: May 20, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

  • Premature ejaculation, severe ED, and hypoactive sexual desire disorder require innovative therapeutic solutions.
  • The sexual medicine field is characterized by both challenges and a commitment to patient-centered innovation.
  • Conclusions:

    • The sexual medicine field, despite facing economic and research-related hurdles, is poised for continued development.
    • Addressing unmet needs in sexual health remains a priority for researchers and clinicians.
    • Future research endeavors will focus on novel therapies to enhance patient well-being and sexual function.