Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

Acute Pyelonephritis I: Introduction

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...

Urinary Tract Infection II: Pathophysiology

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

What Every Urogynecologist Should Know About Getting Paid in 2026.

Urogynecology (Philadelphia, Pa.)·2026

Same author

A New Application for Bolt Cutters in Urogynecology: Challenging Removal of an Impacted Pessary.

HCA healthcare journal of medicine·2026

Same author

Nationwide assessment of practice variability in the utilization of hysteropexy at laparoscopic apical suspension for uterine prolapse.

AJOG global reports·2024

Same author

Combined Robotic Ventral Mesh Rectopexy and Sacrocolpopexy for Multicompartmental Pelvic Organ Prolapse.

Diseases of the colon and rectum·2023

Same author

Robotic Ventral Mesh Rectopexy and Sacrocolpopexy.

Diseases of the colon and rectum·2021

Same author

Female Urinary Incontinence Evidence-Based Treatment Pathway: An Infographic for Shared Decision-Making.

Journal of women's health (2002)·2021

Search research articles

Related Experiment Video

Updated: May 20, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

Published on: July 18, 2017

Enterococcus osteomyelitis secondary to pyelonephritis.

Nathan Kow¹, Tanaz R Ferzandi

¹Department of Obstetrics and Gynecology, Division of Urogynecology and Pelvic Reconstructive Surgery, Tufts Medical Center, Boston, MA, USA. kown@ccf.org

International Urogynecology Journal

|July 11, 2012

Summary

This summary is machine-generated.

Enterococcus lumbar osteomyelitis is a rare complication following post-operative pyelonephritis. This case highlights the potential for urinary tract infections to spread hematogenously to the spine.

Related Experiment Videos

Last Updated: May 20, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

Published on: July 18, 2017

Area of Science:

Urology
Infectious Diseases
Neurosurgery

Background:

A 78-year-old female underwent multiple gynecological and urological procedures for uterovaginal prolapse and stress urinary incontinence.
Procedures included laparoscopic-assisted vaginal hysterectomy, uterosacral ligament suspension, tension-free vaginal tape-obturator sling placement, and cystoscopy.

Observation:

The patient developed post-operative back pain, initially attributed to surgical recovery.
Initial investigations revealed enterococcus pyelonephritis, a urinary tract infection.

Findings:

Despite antibiotic treatment for pyelonephritis, persistent back pain prompted further investigation.
Advanced imaging confirmed enterococcus lumbar osteomyelitis at the L1-L2 vertebral level.

Implications:

This case underscores the rare but serious risk of vertebral osteomyelitis secondary to urinary tract infections.
Hematogenous spread from pyelonephritis to the lumbar spine is a critical consideration in post-operative care.
Early recognition and comprehensive work-up are essential for managing such complex infections.