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Updated: May 20, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Sagittal synostosis
1Department of Paediatrics, Dr Gray's Hospital, Elgin, Morayshire, UK. mmasand@nhs.net
Insights
Early diagnosis of sagittal synostosis in infants is vital for successful surgical correction. Prompt intervention in this congenital condition reduces the risk of complications and improves outcomes.
Area of Science:
- Pediatric Neurosurgery
- Congenital Abnormalities
Background:
- Prematurity is a common concern in pediatric clinics.
- Head shape abnormalities can indicate underlying conditions.
Observation:
- A 20-month-old boy born prematurely presented with a long, narrow (scaphocephalic) head shape.
- Head circumference was growing appropriately, but the shape suggested sagittal synostosis.
Findings:
- Skull X-ray confirmed the diagnosis of sagittal synostosis.
- Surgical correction was successfully performed with no major complications.
Implications:
- Early diagnosis and surgical intervention are crucial for minimizing morbidity and mortality associated with sagittal synostosis.
- Timely management of this congenital condition leads to better patient outcomes.
Abstract:
This report concerns a 20-month-old boy, born at 31 weeks of gestation, being followed in the paediatric clinic because of prematurity. He was developing appropriately for his age and his head circumference was growing steadily (between the 75th and 90th centile), with weight and height on the 25th centile. An x-ray of his skull was performed at this stage because of his head shape, which was long and narrow (scaphocephalic)-in itself suggestive of sagittal synostosis. The x-ray confirmed the diagnosis. He was referred to a regional neurosurgical unit for further management. He had a successful surgical correction without major problems. It is to be emphasised that there is a higher morbidity and mortality if reconstructive surgery is not carried out at an early age, and therefore early diagnosis is vital in this congenital condition.
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