Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Malignant middle cerebral artery infarction.

BMJ case reports·2017
Same author

Simultaneous left-sided hypertensive putaminal and thalamic haemorrhages.

BMJ case reports·2017
Same author

Codfish vertebra sign.

BMJ case reports·2017
Same author

Opsoclonus.

BMJ case reports·2017
Same author

Bilateral atherosclerotic internal carotid artery occlusion and recurrent ischaemic stroke.

BMJ case reports·2015
Same author

Cystic meningioma.

BMJ case reports·2015

Related Experiment Video

Updated: May 20, 2026

Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique
08:25

Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique

Published on: June 2, 2016

The striatocapsular infarction and its aftermaths.

Osama S M Amin1, Hero M Zangana, Nawa A Ameen

  • 1Department of Neurology, Sulaimaniya General Teaching Hospital, Sulaimaniya, Iraq. dr.osama.amin@gmail.com

BMJ Case Reports
|July 11, 2012
PubMed
Summary

Middle cerebral artery ischaemic stroke can mimic brain tumors due to variable anatomy, leading to misdiagnosis. This case highlights a striatocapsular infarction initially mistaken for a neoplastic process.

More Related Videos

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Transient Middle Cerebral Artery Occlusion Model of Stroke
05:32

Transient Middle Cerebral Artery Occlusion Model of Stroke

Published on: August 11, 2023

Related Experiment Videos

Last Updated: May 20, 2026

Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique
08:25

Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique

Published on: June 2, 2016

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Transient Middle Cerebral Artery Occlusion Model of Stroke
05:32

Transient Middle Cerebral Artery Occlusion Model of Stroke

Published on: August 11, 2023

Area of Science:

  • Neurology
  • Neuroimaging
  • Vascular Neurology

Background:

  • Ischaemic stroke in the middle cerebral artery (MCA) territory can present atypically.
  • Variable MCA anatomy contributes to unusual clinical and radiographic findings.
  • Misdiagnosis as neoplastic or infectious conditions is a known challenge.

Observation:

  • A 69-year-old comatose woman was initially diagnosed with a brain tumor and significant edema.
  • Referral for further evaluation was prompted by the unusual presentation.
  • The patient presented with coma and was suspected of having a brain tumor.

Findings:

  • Advanced imaging confirmed a large left-sided lenticular nuclear infarction.
  • The infarction extended into adjacent brain regions, consistent with striatocapsular infarction.
  • The final diagnosis was ischaemic stroke, not a neoplastic process.

Implications:

  • Accurate diagnosis of MCA ischaemic stroke is crucial to avoid treatment delays.
  • Awareness of atypical presentations can improve diagnostic accuracy.
  • Distinguishing stroke from tumors is vital for appropriate patient management and therapeutic interventions.