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Updated: May 20, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Management of tibial non-union with tricalcium phosphate and BMP 7
Jonathan Cubitt1, Andrew McAndrew
1Department of Plastic Surgery, Stoke Mandeville Hospital, Aylesbury, UK. jonathan.cubitt@hotmail.co.uk
Abstract:
We present the case of a 30-year-old woman who was referred with an established tibial non-union with a bone defect following a spiral fracture of the tibia. Initial attempts at union with intramedullary fixation and then autograft were unsuccessful. We achieved union by debriding the fibrous tissue and packing the defect with Bone Morphogenetic Protein 7 (Osigraft, Stryker, UK) and a tricalcium phosphate bone void filler (Calstrux, Stryker, UK). We did not use any additional surgical fixation and the patient was supported in an aircast boot.
