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[Comparative analysis on risk factors of axillary lymph node metastasis in Uygur and Han patients with breast cancer]
Ming-shuai Zhang1, Guo-qing Zhang, Wuwalihan Fulati
1Department of Breast Surgery, Affiliated Tumor Hospital, Xinjiang Medical University, Urumqi 830011, China.
Objective:
To comparatively explore the risk factors of axillary lymph node metastasis (ALNM) in Uygur and Han patients with breast cancer.
Methods:
A total of 243 female Han patients and 66 Uygur ones with T(1) stage breast cancer were retrospectively studied by single and multi-factorial Logistic regression analysis.
Results:
The rates of ALNM were 43.94% and 30.86% in Uygur and Han patients respectively. There was statistic difference between them. Statistic differences existed between these two nationals in gravidity and parity. Multi-Factorial Logistic regression analysis showed that age, gravidity and quadrant of tumor localized were the risk factors of ALNM while estrogen receptor (ER)(+) was the protective factor.
Conclusions:
The rate of ALNM in Uygur patients with T(1) stage breast cancer is higher than that in Han counterparts. More gravidity is an influencing factor. Younger age, more gravidity and location of tumor are the high risk factors for ALNM while ER(+) is the protective factor.