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Updated: May 20, 2026

The Intra-Aortic Balloon Pump
Published on: February 5, 2021
Heparin-free management of intra-aortic balloon pump after cardiac surgery
Alexander Kogan1, Sergey Preisman, Leonid Sternik
1Department of Cardiothoracic Surgery, Sheba Medical Center, Tel Hashomer, affiliated with the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. alexanderkogan140@hotmail.com
Insights
Heparin-free management after intra-aortic balloon pump (IABP) insertion in cardiac surgery patients showed low rates of thromboembolic complications and reduced bleeding risk. This approach may be a safe alternative to routine heparin use.
Area of Science:
- Cardiology
- Vascular Surgery
- Anesthesiology
Background:
- Anticoagulation with heparin is standard for intra-aortic balloon pump (IABP) use to prevent thrombosis.
- Heparin increases bleeding risk, especially post-cardiac surgery.
- Investigated safety of heparin-free management in cardiac surgery patients with IABP.
Purpose of the Study:
- To evaluate the safety and efficacy of a heparin-free management strategy in patients requiring IABP after cardiac surgery.
- To assess the incidence of thrombotic and hemorrhagic complications in this patient cohort.
Main Methods:
- Prospective study of 203 consecutive cardiac surgery patients receiving perioperative IABP support (August 2004 - December 2011).
- Patients were managed without heparin and monitored for thrombotic and hemorrhagic complications.
- Group I: IABP < 24 hours post-surgery (n=81); Group II: IABP > 24 hours post-surgery (n=122).
Main Results:
- Overall vascular complications occurred in 3.4% (7/203) of patients (2 in Group I, 5 in Group II), primarily minor limb ischemia.
- No major bleeding complications were reported.
- Minor bleeding complications occurred in 4.2% (8/203) of patients.
Conclusions:
- Heparin-free management in cardiac surgery patients with IABP support is associated with a low rate of thromboembolic complications compared to historical data.
- This strategy may reduce hemorrhagic complications while maintaining a low risk of thrombosis.
- Routine heparin use may not be necessary for all patients requiring IABP after cardiac surgery.
Background:
Anticoagulation with heparin is recommended in patients with an intra-aortic balloon pump (IABP) to prevent thrombosis and embolization. However, anticoagulation increases the risk of bleeding, particularly in the early postoperative period after cardiac surgery. We investigated the safety of heparin-free management after IABP insertion in patients who underwent cardiac surgery.
Methods:
We studied 203 consecutive patients who received perioperative IABP support between August 2004 and December 2011. All patients were managed without heparin and were followed for thrombotic and/or hemorrhagic complications.
Results:
Patients were divided into two groups, according to time of IABP treatment following surgery. Group I, 81 patients (39.9%) were treated less than 24 hours following surgery and Group II, 122 patients (60.1%) were treated more than 24 hours following surgery. Vascular complications developed in seven patients (3.4%), two in Group I and five in Group II. Three patients had major and four had minor limb ischemia. There were no major bleeding complications, but minor bleeding complications were observed in eight patients (4.2%).
Conclusion:
In patients undergoing cardiac surgery with IABP support, the rate of thromboembolic complications was relatively low compared to historical controls. Heparin-free management may reduce the risk of hemorrhagic complications, with a low risk of thrombotic complications. Heparin should not be routinely used in patients requiring IABP after cardiac surgery.
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