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Validation of the Spanish version of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E)
Daniela Di Capua1, Maria Eugenia Garcia-Garcia, Abilio Reig-Ferrer
1Epilepsy Unit, Hospital Clinico San Carlos, Madrid, Spain. danidicapua@gmail.com
Introduction:
To translate and validate into Spanish (Spain) the screening instrument of major depressive episodes (MDEs), Neurological Disorders Depression Inventory in Epilepsy (NDDI-E), in patients with epilepsy.
Methods:
A total of 121 outpatients, aged 18 years and older, with a diagnosis of epilepsy were included. The diagnosis of a current major depressive episode (MDE) was established with the Mini International Neuropsychiatric Interview (MINI).
Results:
A diagnosis of current MDE was established in 20% of the patients with the MINI. Receiver operator characteristics (ROC) analysis showed an area under the curve of 0.89, with an internal consistency of 0.78. At a cutoff score >13, 22% of patients were considered to suffer from MDE with the NDDI-E (sensitivity: 84%; specificity: 78%; positive predictive value: 64.7%; and negative predictive value: 92.2%).
Discussion:
The Spanish-Spain version of the NDDI-E appears to be a good screening instrument to identify MDE.
