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Updated: May 20, 2026

Simulation of Human-induced Vibrations Based on the Characterized In-field Pedestrian Behavior
Published on: April 13, 2016
Characterization of frequency-dependent responses of the vascular system to repetitive vibration
Kristine Krajnak1, G Roger Miller, Stacey Waugh
1Engineering and Controls Technology Branch, National Institute for Occupational Safety and Health, Health Effects Laboratory Division, Morgantown, WV 26505, USA. ksk1@cdc.gov
Objective:
Occupational exposure to hand-transmitted vibration can result in damage to nerves and sensory loss. The goal of this study was to assess the frequency-dependent effects of repeated bouts of vibration on sensory nerve function and associated changes in nerves.
Methods:
The tails of rats were exposed to vibration at 62.5, 125, or 250 Hz (constant acceleration of 49 m/s2) for 10 days. The effects on sensory nerve function, nerve morphology, and transcript expression in ventral tail nerves were measured.
Results:
Vibration at all frequencies had effects on nerve function and physiology. However, the effects tended to be more prominent with exposure at 250 Hz.
Conclusion:
Exposure to vibration has detrimental effects on sensory nerve function and physiology. However, many of these changes are more prominent at 250-Hz exposure than at lower frequencies.
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