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Rapid fabrication of complex 3D extracellular microenvironments by dynamic optical projection stereolithography
A Ping Zhang1, Xin Qu, Pranav Soman
1Department of NanoEngineering, University of California, San Diego, CA 92093, USA. zhangap@zju.edu.cn
Advanced Materials (Deerfield Beach, Fla.)
|July 13, 2012
Abstract:
The topographic features of the extracelluar matrix (ECM) lay the foundation for cellular behavior. A novel biofabrication method using a digital-mirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated. This robust and versatile platform can generate complex biomimetic scaffolds within seconds. Such 3D scaffolds have promising potentials for studying cell interactions with microenvironments in vitro and in vivo.
