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Updated: May 20, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Papillary thyroid-type carcinoma arising from struma ovarii
Jerome Rebollos Barrera1, Leonido Andrade Manalo, Frances Lina Lantion Ang
1Department of Medicine, Philippine General Hospital, Manila, Philippines. jrom0330@yahoo.com
Abstract:
Malignant transformation of benign monodermal teratoma is a rare presentation of struma ovarii. A 41-year-old Filipina presented with 1-year history of recurrent lower abdominal pain, abdominal swelling and vomiting. Ultrasound of the abdomen revealed a large cystic abdomino-pelvic mass densely adherent to the intestinal and uterine wall with moderate ascitis. The patient underwent total abdominal hysterectomy and bilateral salphingo-oophorectomy and histopathology showed papillary thyroid-type carcinoma arising from the left struma ovarii. She underwent total thyroidectomy, postoperative radioactive iodine ablation and maintained on levothyroxine suppressive therapy. She is now on regular follow-up for monitoring of possible tumour recurrence and metastasis.
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