Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Molecular Shapes01:18

Molecular Shapes

Molecules have characteristic shapes that are crucial for their function. The arrangement of various electron groups around the central atom dictates their molecular geometry. Electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between the electron pairs by maximizing the distance between them. The valence electrons form either bonding pairs, located primarily between bonded atoms, or lone pairs.
Two regions of electron density in a diatomic...
Molecular Shape and Polarity03:37

Molecular Shape and Polarity

Dipole Moment of a Molecule
Molecular Models02:00

Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
Molecular Geometry and Dipole Moments02:36

Molecular Geometry and Dipole Moments

The VSEPR theory can be used to determine the electron pair geometries and molecular structures as follows:
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

VSEPR Theory for Determination of Electron Pair Geometries
VSEPR Theory02:37

VSEPR Theory

Valence shell electron-pair repulsion theory (VSEPR theory) enables us to predict the molecular structure around a central atom from an examination of the number of bonds and lone electron pairs in its Lewis structure. The VSEPR model assumes that electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between these electron pairs by maximizing the distance between them. The electrons in the valence shell of a central atom form either bonding...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multivalent-Anion-Induced Inversion of Chiroptical Signals in a Cyanine Dye Bound to Nanotubular Supramolecular Assemblies.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Highly Selective Separation of Hydrogen Isotopes via the Construction of Ionic-Bonded Organic Frameworks.

Analytical chemistry·2026
Same author

Environmentally benign and sustainability-optimized extraction of alkaloids from Tetradium ruticarpum using custom-designed deep eutectic solvents.

Journal of chromatography. A·2026
Same author

Synthesis of C18-modified radial mesoporous core-shell silica microspheres with tunable shell thickness for ultra-high performance liquid chromatography.

Journal of chromatography. A·2026
Same author

Nanosilica-Cross-Linked Poly(N-(2-Hydroxyethyl) Acrylamide)Hybrid Hydrogel for Remediation of Cr(VI) Ions and Methylene Blue Contaminated Water.

Chemistry, an Asian journal·2026
Same author

Propylsulfonic acid-bonded silica stationary phase through mercapto oxidation for chromatographic separation of rare earth elements.

Analytical and bioanalytical chemistry·2026

Related Experiment Video

Updated: May 20, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

Molecular shape recognition through self-assembled molecular ordering: evaluation with determining architecture and

Abul K Mallik1, Hongdeng Qiu, Tsuyoshi Sawada

  • 1Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555, Japan.

Analytical Chemistry
|July 14, 2012
PubMed
Summary

A novel silica-based organic phase (Sil-FIP) utilizing molecular gel-forming compounds demonstrates superior chromatographic performance. Its integrated functional groups provide exceptional molecular shape selectivity, outperforming traditional alkyl phases.

More Related Videos

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
16:24

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Published on: August 2, 2012

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Related Experiment Videos

Last Updated: May 20, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
16:24

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Published on: August 2, 2012

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Area of Science:

  • Chromatography
  • Materials Science
  • Organic Chemistry

Background:

  • Traditional alkyl phases (C30, C18) are widely used in chromatography.
  • There is a need for novel stationary phases with enhanced selectivity.
  • Molecular gel-forming compounds offer potential for unique chromatographic properties.

Purpose of the Study:

  • To investigate the relationship between the structure of a novel molecular gel-forming compound-based organic phase (Sil-FIP) and its chromatographic performance.
  • To compare the performance of Sil-FIP with established alkyl phases.
  • To elucidate the mechanism behind Sil-FIP's high molecular shape selectivity.

Main Methods:

  • Chemical design and synthesis of the Sil-FIP phase on silica.
  • Characterization using temperature-dependent circular dichroism (CD) and NMR spectroscopy (13C CP/MAS, 29Si CP/MAS, 1H NMR).
  • Chromatographic evaluation using standard reference materials and selectivity test mixtures.

Main Results:

  • Sil-FIP exhibits high orientation and selectivity due to integrated weak interaction sites and multiple solute interactions.
  • NMR and CD studies reveal the self-assembling nature, conformational dynamics, and chirality of the gel-forming compounds.
  • Sil-FIP demonstrates very high molecular shape selectivity, surpassing reference alkyl phases.

Conclusions:

  • The integrated and ordered functional groups within the Sil-FIP phase are the primary drivers of its exceptional shape selectivity.
  • Sil-FIP represents a promising new stationary phase for advanced chromatographic separations.
  • Spectroscopic and chromatographic data provide critical insights into surface morphology and molecular recognition.