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Updated: May 20, 2026

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A Mouse Model of Ankle-Subtalar Complex Joint Instability
Published on: October 28, 2022
Association between ankle fractures and obesity.
Christy M King1, Graham A Hamilton, Mathew Cobb
1Kaiser San Francisco Bay Area Foot and Ankle Residency Program, Oakland, CA 94611, USA. christy.m.king@kp.org
Summary
Obesity increases the risk of severe ankle fractures, specifically Weber C fibula fractures. Younger age and male sex also correlate with higher fracture severity in this study.
Area of Science:
- Orthopedics
- Trauma Surgery
- Public Health
Background:
- Obesity is a significant public health concern in the US, linked to musculoskeletal issues.
- Ankle fractures, particularly Weber C type, involve the distal fibula and can lead to instability.
- Understanding risk factors for severe ankle fractures is crucial for effective treatment and prevention.
Purpose of the Study:
- To investigate the association between obesity and the severity of ankle fractures.
- To determine if body mass index (BMI) correlates with specific Weber classifications of ankle fractures.
Main Methods:
- Retrospective review of 280 patient radiographs with ankle fractures.
- Classification of fractures using the Weber system (A, B, C).
- Analysis of associations between BMI (≥30 kg/m²), gender, age, diabetes, tobacco use, and osteoporosis with fracture severity.
Main Results:
- Obesity (BMI ≥30 kg/m²) was associated with a higher likelihood of Weber C fractures (OR 1.78).
- Younger age (≤25 years) showed a strong association with more severe fractures (OR 3.97).
- Male gender also correlated with increased odds of severe ankle fractures (OR 1.74).
- Diabetes, osteoporosis, and tobacco use were not significantly linked to fracture severity.
Conclusions:
- Obesity is a significant risk factor for sustaining more severe distal fibula fractures (Weber C).
- Younger age and male sex are also associated with increased risk of severe ankle fractures.
- These findings highlight the importance of weight management in reducing the incidence and severity of ankle fractures.
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