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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Institutional differences in endovascular aneurysm repair and aneurysm morphology
Andrew L Tambyraja1, Julio A Rodriguez-Lopez, Venkatesh Ramaiah
1Arizona Heart Institute, Phoenix, AZ 85006, USA. andrew.tambyraja@ed.ac.uk
World Journal of Surgery
|July 14, 2012
Summary
British patients undergoing endovascular aneurysm repair (EVAR) present with more complex aortic aneurysm morphology compared to American patients. These anatomical differences may influence EVAR application rates between institutions.
Area of Science:
- Vascular Surgery
- Medical Imaging
- Comparative Effectiveness Research
Background:
- Significant institutional variability exists in the application of endovascular aneurysm repair (EVAR).
- This study addresses this by comparing patient-specific variables between a high-volume North American center and a UK institution.
Purpose of the Study:
- To compare patient and aneurysm characteristics between American and British cohorts undergoing treatment for intact infrarenal aortic aneurysms.
- To investigate potential anatomical factors contributing to differing EVAR utilization rates.
Main Methods:
- A comparative analysis of 100 consecutive patients from each of two institutions (North America and UK).
- Patient demographics and aneurysm morphology were assessed using computed tomography (CT) scans.
- Measurements followed Society for Vascular Surgery (USA) reporting standards.
Main Results:
- British patients presented with significantly larger mean aneurysm diameters (64 mm vs. 55 mm) and more angulated aneurysms (>60° in 22% vs. 11%).
- The infrarenal aortic neck was shorter (mean 21 mm vs. 25 mm) and common iliac arteries were larger in the British cohort.
- All American patients received EVAR, whereas only 11% of British patients did.
Conclusions:
- British patients exhibit a more advanced pattern of aortic aneurysm morphology compared to their American counterparts.
- These morphological differences may partially explain the observed variability in EVAR application between the two countries.
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