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Updated: May 20, 2026

Seeded Synthesis of CdSe/CdS Rod and Tetrapod Nanocrystals
Published on: December 11, 2013
Synthesis and functionalization of CdSe/ZnS QDs using the successive ion layer adsorption reaction and
Ana Sofia Miguel1, Christopher Maycock, Abel Oliva
1Organic Synthesis Laboratory, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal. sofmig@itqb.unl.pt
Abstract:
Detailed protocols for the preparation of CdSe nanocrystals coated with a multishell structure of ZnS and their surface modification based on the successive ion layer adsorption and reaction method are described. The first phase of the synthesis produces a hydrophobic surface consisting of a TOPO/HDA ligand mixture. This is followed by a surface modification of the quantum dots (QDs) with 3-mercaptopropionic acid by the phase transfer method. The modified QDs become soluble in aqueous systems such as water or buffers for further biological applications.
