Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...
Drug Accumulation During Multiple Dosing: Repetitive IV Injections01:21

Drug Accumulation During Multiple Dosing: Repetitive IV Injections

Calculating drug dosage and accumulation in multiple-dose regimens is crucial for achieving therapeutic efficacy while avoiding toxicity. This involves determining the plasma drug concentrations over time to optimize dosing schedules. The principle of superposition is fundamental in this process, allowing for the prediction of drug concentration in plasma following multiple doses based on single-dose data.The principle of superposition asserts that the plasma concentration-time curves from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Caregiver Reports of Lucid Episodes in Alzheimer's Dementia and Lewy Body Dementias.

Journal of geriatric psychiatry and neurology·2026
Same author

Effects of sandtray therapy on the life review, mental health, and cognitive ability of the community-dwelling older adults in Taiwan- A mixed-methods study.

International psychogeriatrics·2026
Same author

A Structured Consent Framework for Research of Electroconvulsive Therapy in Advanced Dementia: Consent Process for the ECT-AD Trial.

The journal of ECT·2026
Same author

Artificial intelligence for predicting hospital admissions from the emergency department: a prospective, quasi-experimental study.

Nature communications·2026
Same author

Delirium and lucid episodes in dementia: Associations with anticipatory grief and caregiver stressors.

International psychogeriatrics·2026
Same author

Adoption of unsedated transoral wireless pH capsule at a Veterans Affairs hospital: a feasibility study.

iGIE : innovation, investigation and insights·2026
Same journal

Association of intervention fidelity and outcomes in implementation of the Thrive transitional care program for Medicaid-insured individuals.

Journal of hospital medicine·2026
Same journal

Association of 1- versus 2-week faculty rotations for resident teaching services on patient outcomes, learning environment and burnout.

Journal of hospital medicine·2026
Same journal

The 5R's of large language model-assisted diagnosis: A practical framework for hospitalists.

Journal of hospital medicine·2026
Same journal

Overnight consult message volume and patterns to pediatric subspecialty fellows.

Journal of hospital medicine·2026
Same journal

Family and friends perspectives on communication barriers and patient social isolation in Canadian hospitals.

Journal of hospital medicine·2026
Same journal

Supporting graduate medical trainees through parental leave: Best practices for program success.

Journal of hospital medicine·2026
See all related articles

Related Experiment Video

Updated: May 20, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

Multiple admissions for alcohol withdrawal.

Scott A Larson1, M Caroline Burton, Deanne T Kashiwagi

  • 1Department of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.

Journal of Hospital Medicine
|July 14, 2012
PubMed
Summary
This summary is machine-generated.

Patients with alcohol withdrawal syndrome (AWS) who have lower education, more comorbidities, use other drugs, or have psychiatric issues are more likely to be readmitted. Identifying these risk factors can improve patient care and reduce hospital readmissions.

More Related Videos

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
05:40

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Related Experiment Videos

Last Updated: May 20, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
05:40

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Area of Science:

  • Internal Medicine
  • Addiction Medicine
  • Public Health

Background:

  • Alcohol withdrawal syndrome (AWS) is a common reason for hospital admission.
  • Recidivism in AWS patients presents a significant challenge to healthcare systems.
  • Identifying predictors of multiple AWS admissions is crucial for effective patient management.

Purpose of the Study:

  • To determine risk factors associated with multiple hospital admissions for AWS.
  • To compare demographic and clinical variables between single and multiple AWS admission groups.

Main Methods:

  • Retrospective study of 322 patients admitted for AWS between 2006-2008.
  • Analysis of patient records comparing single vs. multiple admissions.
  • Statistical comparison of demographic and clinical data.

Main Results:

  • 44% of patients had multiple AWS admissions.
  • Multiple admissions were linked to lower education, higher comorbidity scores (Charlson index), positive non-alcohol drug screens, psychiatric comorbidities, and higher peak AWS severity (CIWA-Ar scores).

Conclusions:

  • Specific demographic and clinical factors predict multiple AWS admissions.
  • Targeted, multidisciplinary interventions at initial admission are needed.
  • Addressing these factors can help reduce high rates of AWS recidivism.