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In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...

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Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...

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Updated: May 20, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Interruption handling strategies during paediatric medication administration.

Lacey Colligan¹, Ellen J Bass

¹Division of Neonatology, University of Virginia, Charlottesville, VA 22908, USA. rlc7z@virginia.edu

BMJ Quality & Safety

|July 14, 2012

Summary

Pediatric nurses use sophisticated strategies to manage interruptions during medication administration, balancing patient safety and workflow efficiency. Understanding these methods can inform interventions to reduce medication errors.

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Area of Science:

Healthcare delivery
Nursing practice
Patient safety

Background:

Interruptions are common in hospitals and can cause medication errors during administration.
Effective interruption management is crucial for patient safety and efficient healthcare delivery.

Purpose of the Study:

To identify and analyze interruption management strategies used by pediatric nurses during medication administration.
To understand factors influencing nurses' choice of interruption handling strategies.

Main Methods:

Semi-structured interviews with pediatric nurses in an inpatient setting.
Analysis of nurses' verbal protocols for use case scenarios.
On-the-job observations to confirm and refine interruption handling frameworks.

Main Results:

Four interruption handling strategies were identified: suspending the primary task, multi-tasking, mediating the interruption, and blocking the interruption.
Nurses dynamically assess tasks, prioritizing based on risk and workflow efficiency.
Strategy selection is influenced by task-specific and experience-related factors.

Conclusions:

Pediatric nurses employ advanced strategies to manage interruptions, ensuring patient safety and work efficiency.
Supporting these strategies through improved processes, tools, and education can enhance healthcare system resilience.