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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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Related Experiment Video

Updated: May 20, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

Published on: July 28, 2020

Mouse models can predict cancer therapy.

W Michael Kuehl¹

¹National Cancer Institute.

|July 14, 2012

Summary

This summary is machine-generated.

A new genetically engineered mouse model accurately predicts multiple myeloma drug activity. This model shows promise for evaluating drug efficacy before clinical trials, aiding future treatment development.

Area of Science:

Hematology
Oncology
Translational Medicine

Background:

Multiple myeloma is a hematologic malignancy with unmet therapeutic needs.
Predictive preclinical models are crucial for efficient drug development in multiple myeloma.

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