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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

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Published on: June 2, 2014

Recurrent syncope and chronic ear pain.

Andrew Clegg1, Luis Daverede, Winson Wong

  • 1Academic Unit of Elderly Care and Rehabilitation, Bradford Institute for Health Research, Bradford, UK. andrewpaulclegg@yahoo.co.uk

BMJ Case Reports
|July 14, 2012
PubMed
Summary
This summary is machine-generated.

A skull base infection caused a patient's recurrent syncope and postural hypotension. Prompt antibiotic treatment resolved the infection and related symptoms, highlighting the link between infection and cardiovascular events.

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Area of Science:

  • Infectious Diseases
  • Neurology
  • Otolaryngology

Background:

  • Skull base infections are rare but can present with diverse neurological symptoms.
  • Carotid sinus involvement in infection can mimic cardiovascular events like syncope.

Observation:

  • An elderly male presented with syncope, postural hypotension, and right ear pain.
  • MRI revealed a nasopharyngeal soft tissue abnormality; biopsies showed bacterial infection (Pseudomonas, diphtheroids).

Findings:

  • Skull base infection involving the carotid sinus was diagnosed as the cause of syncope and hypotension.
  • Intravenous meropenem for 12 weeks led to infection resolution and symptom improvement.

Implications:

  • This case underscores the importance of considering infectious etiologies for unexplained syncope and orthostatic hypotension.
  • Early diagnosis and targeted antibiotic therapy are crucial for managing skull base infections and associated complications.