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Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
Published on: October 2, 2014
Primary cardiac tumours: a single-center 41-year experience
Christina Maria Steger1, Thomas Hager, Elfriede Ruttmann
1Department of Pathology, Innsbruck Medical University, Müllerstraße 44, 6020 Innsbruck, Austria.
ISRN Cardiology
|July 14, 2012
Summary
Primary cardiac tumors are rare, with left atrial myxomas being most common. Surgical resection is recommended for mobile tumors to prevent embolization, and recurrence is very low.
Area of Science:
- Cardiovascular Surgery
- Cardiac Oncology
- Pathology
Background:
- Primary cardiac tumors are rare, with left atrial myxomas being the most frequent type.
- Surgical intervention is typically indicated for mobile tumors with embolic potential.
Purpose of the Study:
- To analyze the incidence, types, and outcomes of primary cardiac tumor resections.
- To evaluate the recurrence rates following surgical treatment of cardiac tumors.
Main Methods:
- Retrospective analysis of 78 patients who underwent tumourectomy for primary cardiac tumors.
- Data collected included patient demographics, tumor type, and follow-up for recurrence.
- Tumor types included myxomas, papillary fibroelastomas, hemangiomas, chemodectomas, and rhabdomyosarcomas.
Main Results:
- A total of 78 patients (0.45% of heart surgery patients) underwent tumourectomy.
- Left and right atrial myxomas constituted the majority of tumors (63 patients).
- The mean patient age was 54.29 years, with a female predominance (67.95%); tumor recurrence was rare (2.56%).
Conclusions:
- Primary cardiac tumors are uncommon, with myxomas being the most prevalent type.
- Surgical resection is effective, with a very low recurrence rate, highlighting the importance of timely intervention.
- This study underscores the importance of early detection and surgical management for primary cardiac tumors.