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Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Allergic Reactions02:06

Allergic Reactions

Overview
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

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Related Experiment Video

Updated: May 20, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Chapter 5: Allergic rhinitis.

Ashraf Uzzaman, Rachel Story

    Allergy and Asthma Proceedings
    |July 17, 2012
    PubMed
    Summary
    This summary is machine-generated.

    Allergic rhinitis, affecting up to 40% of the population, causes significant quality of life issues. Management includes allergen avoidance, pharmacotherapy, and immunotherapy for symptom relief.

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    Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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    Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

    Published on: March 3, 2023

    Related Experiment Videos

    Last Updated: May 20, 2026

    Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
    06:08

    Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

    Published on: September 22, 2023

    Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
    08:47

    Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

    Published on: March 3, 2023

    Area of Science:

    • Immunology
    • Otolaryngology
    • Allergy and Immunology

    Background:

    • Rhinitis is a nasal inflammatory disorder with diverse causes, including allergic reactions.
    • Allergic rhinitis impacts up to 40% of the population, leading to nasal symptoms and reduced quality of life.
    • Nasal mucosa vascularity and autonomic nervous system influence nasal congestion and secretions.

    Purpose of the Study:

    • To review the causes, symptoms, and management strategies for allergic rhinitis.
    • To discuss the impact of allergic rhinitis on daily life and work.
    • To outline current pharmacotherapy and immunotherapy options for allergic rhinitis.

    Main Methods:

    • Literature review of rhinitis and allergic rhinitis causes, pathophysiology, and treatments.
    • Analysis of current pharmacological and non-pharmacological management approaches.
    • Synthesis of evidence for treatment efficacy in mild and severe allergic rhinitis.

    Main Results:

    • Allergic rhinitis presents with nasal itching, congestion, sneezing, and rhinorrhea, impacting sleep and performance.
    • Pharmacotherapy includes antihistamines, corticosteroids, anticholinergic agents, and leukotriene antagonists.
    • Allergen immunotherapy is the sole disease-modifying treatment, while combination therapy offers superior relief.

    Conclusions:

    • Effective management of allergic rhinitis requires a combination of allergen avoidance, pharmacotherapy, and patient education.
    • Intranasal corticosteroids are preferred for persistent moderate/severe allergic rhinitis.
    • Allergen immunotherapy provides a disease-modifying approach for allergic rhinitis.