Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Allergic Reactions

Allergic Reactions

Chronic Pharyngitis

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Allergic Reactions: Anaphylaxis

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...

Asthma: Pathogenesis and Management

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A rare case of lactation-associated anaphylaxis.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2026

Same author

Baseline disease characteristics among patients with chronic rhinosinusitis with nasal polyps in AROMA: A global registry study.

Allergy and asthma proceedings·2025

Same author

Induction of a mismatch repair deficient genotype by tailored chemical mutagenesis in experimental models of cancer.

Cancer cell·2025

Same author

Neoantigen immunogenicity landscapes and evolution of tumor ecosystems during immunotherapy with nivolumab.

Nature medicine·2024

Same author

Increased Synthetic Cytotoxicity of Combinatorial Chemoradiation Therapy in Homologous Recombination Deficient Tumors.

International journal of radiation oncology, biology, physics·2024

Same author

Identification of Cardiac Patients Based on the Medical Conditions Using Machine Learning Models.

Computational intelligence and neuroscience·2022

Same journal

Key factors in the diagnosis of sesame allergy in children.

Allergy and asthma proceedings·2026

Same journal

Immunoglobulin E-mediated pumpkin seed allergy in children: Case series and narrative review with a structured literature search.

Allergy and asthma proceedings·2026

Same journal

Predictors of delayed treatment-free remission with omalizumab in chronic spontaneous urticaria.

Allergy and asthma proceedings·2026

Same journal

The digital front door: A national analysis of U.S. allergy and immunology fellowship program web sites.

Allergy and asthma proceedings·2026

Same journal

The impact of dietary patterns on the risk of asthma in children.

Allergy and asthma proceedings·2026

Same journal

The alpha-gal syndrome: Understanding the role of tick bites, and the delays in severe anaphylaxis.

Allergy and asthma proceedings·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 20, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Chapter 6: Nonallergic rhinitis.

Rachna Shah, Kris G McGrath

Allergy and Asthma Proceedings

|July 17, 2012

Summary

This summary is machine-generated.

Nonallergic rhinitis involves non-IgE mediated nasal symptoms like congestion and rhinorrhea. Differentiating it from allergic rhinitis involves a thorough history, physical exam, and potentially skin testing.

More Related Videos

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Related Experiment Videos

Last Updated: May 20, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Area of Science:

Otolaryngology
Allergy and Immunology

Background:

Nonallergic rhinitis encompasses non-IgE mediated conditions presenting with nasal congestion, rhinorrhea, sneezing, and postnasal discharge.
Etiologies are broadly categorized into inflammatory (postinfectious, nasal polyps, eosinophilic) and noninflammatory (idiopathic, medication-induced, hormonal, systemic disease, structural defects).

Purpose of the Study:

To outline the diverse causes and diagnostic approaches for nonallergic rhinitis.
To differentiate nonallergic rhinitis from allergic rhinitis.

Main Methods:

Diagnosis relies on a detailed patient history and physical examination, including nasal cavity inspection.
Skin testing for aeroallergens aids in distinguishing nonallergic from allergic rhinitis by assessing IgE antibody presence.

Main Results:

Nonallergic rhinitis presents with varied symptoms and triggers, distinct from allergic rhinitis which involves pruritus.
Diagnostic evaluation includes differentiating between inflammatory and noninflammatory causes.

Conclusions:

Accurate diagnosis of nonallergic rhinitis is crucial for appropriate management.
Pharmacotherapy options include topical antihistamines, intranasal steroids, anticholinergics, and oral decongestants, with careful consideration of patient comorbidities.