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Updated: May 20, 2026

Controlled-release of Chlorine Dioxide in a Perforated Packaging System to Extend the Storage Life and Improve the Safety of Grape Tomatoes
Published on: April 7, 2017
Lack of enhanced effect of a chlorine dioxide-based cleaning regimen on environmental contamination with Clostridium
S D Goldenberg1, A Patel, D Tucker
1Centre for Clinical Infection and Diagnostic Research, Guy's & St Thomas' NHS Foundation Trust and King's College, London, UK. simon.goldenberg@gstt.nhs.uk
Abstract:
Spores of Clostridium difficile may play a significant role in transmission of disease within the healthcare environment and are resistant to a variety of detergents and cleaning fluids. A range of environmental cleaning agents has recently become available, many of which claim to be sporicidal. We investigated the effect of changing to a chlorine dioxide-based cleaning regimen on C. difficile environmental contamination and patient infection rates. The prevalence of environmental contamination was unaffected with a rate of 8% (9/120) before and 8% (17/212) following the change. Rates of patient infection were also unchanged during these periods.
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