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Cost-effectiveness of routine coagulation testing in the evaluation of chest pain in the ED
Erik Kochert1, Lawrence Goldhahn, Ian Hughes
1Department of Emergency Medicine, York Hospital, York, Pennsylvania, USA. ekochert@wellspan.org
Insights
Routine coagulation testing for chest pain patients in the emergency department (ED) is not cost-effective. This practice should be avoided to reduce unnecessary healthcare costs and improve resource allocation.
Area of Science:
- Emergency Medicine
- Clinical Pathology
- Health Economics
Background:
- Chest pain accounts for approximately 5% of US emergency department (ED) visits.
- Coagulation testing is frequently performed during the ED evaluation of chest pain patients.
Purpose of the Study:
- To assess the cost-effectiveness of routine coagulation testing for patients presenting with chest pain in the ED.
Main Methods:
- Retrospective chart review of 740 patients evaluated for chest pain in a community ED.
- Analysis of coagulation studies ordered, appropriateness of testing, and clinical interventions based on results.
- Defined appropriate testing indications including cirrhosis, known coagulopathy, active bleeding, warfarin use, or ST-elevation myocardial infarction.
Main Results:
- Coagulation studies were ordered in 55% of patients (406/740).
- 81% of tested patients (327/406) lacked indications for testing.
- No patients tested without indication required therapeutic intervention, despite one case of clinically significant coagulopathy.
Conclusions:
- Routine coagulation testing in ED chest pain patients is not cost-effective.
- Discontinuation of routine coagulation testing for this patient population is recommended.
Introduction:
Approximately 5% of all US emergency department (ED) visits are for chest pain, and coagulation testing is frequently utilized as part of the ED evaluation.
Objective:
The objective was to assess the cost-effectiveness of routine coagulation testing of patients with chest pain in the ED.
Methods:
We conducted a retrospective chart review of patients evaluated for chest pain in a community ED between August 1, 2010, and October 31, 2010. Charts were reviewed to determine the number and results of coagulation studies ordered, the number of coagulation studies that were appropriately ordered, and the number of patients requiring a therapeutic intervention or change in clinical plan (withholding of antiplatelet/anticoagulant, delayed procedure, or treatment with fresh frozen plasma or vitamin K) based on an unexpected coagulopathy. We considered it appropriate to order coagulation studies on patients with cirrhosis, known/suspected coagulopathy, active bleeding, use of warfarin, or ST-elevation myocardial infarction.
Results:
Of the 740 patients included, 406 (55%) had coagulation studies ordered. Of those 406, 327 (81%) patients with coagulation studies ordered had no indications for testing. One of the 327 patients (0.31%; 95% confidence interval, 0.05%-1.7%) tested without indication had a clinically significant coagulopathy (internationalized normalization ratio >1.5, partial thromboplastin time >50 seconds), but none (0%; 95% confidence interval, 0%-1.2%) of the patients with coagulation testing performed without indication required a therapeutic intervention or change in clinical plan. The cost of coagulation testing in these 327 patients was $16780.
Conclusions:
Coagulation testing on chest pain patients in the ED is not cost-effective and should not be routinely performed.
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