Related Experiment Video
Updated: May 20, 2026

Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases
Published on: June 22, 2012
The future of endothelin research: scientific mentoring and beyond
Matthias Barton1, David M Pollock
1Molecular Internal Medicine, University of Zurich, 8057 Zürich, Switzerland. barton@access.uzh.ch
Abstract:
Endothelium-dependent regulation of vascular tone was one of the key discoveries in physiology in the 1980s, including the characterization of endothelium-derived vasoactive factors such as endothelin. Young investigators, often while starting research as part of their PhD degree, have been instrumental in carrying out the work that led some of the most important discoveries in the endothelin field. This article reviews the importance of mentoring for research in general and for endothelin research in particular, including examples of outstanding young investigators that have been instrumental in some of the key discoveries in the endothelin field. Recognizing scientific excellence among young investigators has a long tradition in the history of the International Conferences on Endothelin. Winners of "Young Investigator Awards" of the past five endothelin conferences (ET-8, ET-9, ET-10, ET-11, and ET-12) are presented, as well as recipients of the "ET-12 Best Presentation Awards" established on the occasion of the Twelfth International Conference on Endothelin ET-12 in Cambridge in September 2011.
Related Concept Videos
Mechanism of Angiogenesis
Regulation of Angiogenesis and Blood Supply
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...

