Related Experiment Video
Updated: May 20, 2026
Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
RIBFIND: a web server for identifying rigid bodies in protein structures and to aid flexible fitting into cryo EM
Arun Prasad Pandurangan1, Maya Topf
1Department of Crystallography/Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, UK. a.pandurangan@mail.cryst.bbk.ac.uk
Motivation:
To better analyze low-resolution cryo electron microscopy maps of macromolecular assemblies, component atomic structures frequently have to be flexibly fitted into them. Reaching an optimal fit and preventing the fitting process from getting trapped in local minima can be significantly improved by identifying appropriate rigid bodies (RBs) in the fitted component.
Results:
Here we present the RIBFIND server, a tool for identifying RBs in protein structures. The server identifies RBs in proteins by calculating spatial proximity between their secondary structural elements.
Availability:
The RIBFIND web server and its standalone program are available at http://ribfind.ismb.lon.ac.uk.
Contact:
a.pandurangan@mail.cryst.bbk.ac.uk
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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