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Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: May 20, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Practical landmarks for visual field disability in glaucoma.

Luke J Saunders¹, Richard A Russell, David P Crabb

¹Department of Optometry and Visual Science, City University London, Northampton Square, London, UK.

The British Journal of Ophthalmology

|July 17, 2012

Summary

This summary is machine-generated.

Better eye mean deviation (MD) accurately predicts legal fitness to drive (LFTD) in glaucoma patients. This finding helps establish visual field disability benchmarks for driving assessments.

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Published on: July 21, 2020

Area of Science:

Ophthalmology
Optometry
Driving Safety

Background:

Glaucoma can impair visual fields (VF), potentially affecting driving ability.
Assessing legal fitness to drive (LFTD) in glaucoma patients requires understanding VF limitations.

Purpose of the Study:

To determine if mean deviation (MD) from automated perimetry correlates with the VF component of LFTD in glaucoma patients.
To evaluate the predictive capability of MD for driving fitness.

Main Methods:

Retrospective analysis of 2604 patients with bilateral VF damage using monocular 24-2 VFs.
Integrated visual fields calculated as a surrogate for LFTD based on UK driving licence criteria.
Comparison of better eye MD (BEMD), worse eye MD (WEMD), and combined MD measures for LFTD prediction.

Main Results:

BEMD demonstrated high diagnostic accuracy for LFTD (AUC: 96.2%).
MD from both eyes provided no significant additional predictive power (AUC: 96.4%).
Probability of Failure (PoF) for LFTD was 70% at ≤-10 dB BEMD and 92% at ≤-14 dB BEMD.

Conclusions:

A strong relationship exists between BEMD and LFTD in glaucoma patients.
Probability of Failure values linked to MD offer practical benchmarks for VF disability impacting driving.
BEMD is a reliable indicator for assessing driving fitness in glaucoma.