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Updated: May 20, 2026
05:07
Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
(4-Fluoro-phen-yl)(1H-pyrrol-2-yl)methan-one
Summary
The dihedral angle between the pyrrole and benzene rings in the C(11)H(8)FNO molecule is 49.16 degrees. Adjacent molecules form inversion dimers through N-H⋯O hydrogen bonds in the crystal structure.
Area of Science:
- Crystallography
- Organic Chemistry
- Molecular Structure
Background:
- Understanding the three-dimensional arrangement of atoms in organic molecules is crucial for predicting their properties and reactivity.
- Crystal engineering utilizes intermolecular interactions to design materials with specific characteristics.
Purpose of the Study:
- To determine the precise molecular geometry of the C(11)H(8)FNO molecule.
- To investigate the intermolecular interactions and crystal packing in the solid state.
Main Methods:
- Single-crystal X-ray diffraction was employed to analyze the crystal structure.
- Geometric parameters, including dihedral angles and bond lengths/angles, were accurately measured.
Main Results:
- The dihedral angle between the pyrrole and benzene rings was found to be 49.16(6)°.
- Adjacent molecules are connected by a network of N-H⋯O hydrogen bonds, forming characteristic inversion dimers in the crystal lattice.
Conclusions:
- The determined molecular structure provides fundamental data for the C(11)H(8)FNO compound.
- The hydrogen bonding interactions dictate the observed crystal packing and supramolecular assembly.
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