2-[4-(Chloro-meth-yl)phen-oxy]-4,6-dimeth-oxy-pyrimidine

Area of Science:

• Medicinal Chemistry
• Organic Chemistry
• Crystallography

Background:

• Pyrimidine derivatives are known for diverse biological activities.
• The search for novel bioactive molecules is ongoing.
• Structure-activity relationships are crucial for drug discovery.

Purpose of the Study:

• To synthesize a novel pyrimidine derivative with potential bioactivity.
• To characterize the synthesized compound's chemical structure.
• To investigate the structural features of new pyrimidine-based molecules.

Main Methods:

• Chemical synthesis of the target compound C(13)H(13)ClN(2)O(3).
• Single-crystal X-ray diffraction for structural determination.
• Analysis of bond angles and dihedral angles.

Main Results:

• Successful synthesis of the title compound C(13)H(13)ClN(2)O(3).
• X-ray crystallography revealed a C-O-C angle of 119.87°.
• The dihedral angle between pyrimidine and benzene rings was determined to be 64.2°.

Conclusions:

• The synthesized compound is a novel pyrimidine derivative.
• The determined structural parameters provide insights into its molecular geometry.
• This compound may serve as a lead for developing new bioactive agents.