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Updated: May 20, 2026
14:11
Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
4-(2-Fluoro-pyridin-5-yl)phenol.
Summary
This study details the crystal structure of a fluorinated organic compound, C(11)H(8)FNO. It reveals specific molecular orientations and intermolecular interactions like hydrogen bonds and pi-pi stacking, crucial for understanding material properties.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- Understanding the solid-state structure of organic compounds is essential for predicting their physical and chemical properties.
- Intermolecular interactions, such as hydrogen bonding and pi-pi stacking, significantly influence crystal packing and material behavior.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(11)H(8)FNO.
- To characterize the specific molecular arrangement and intermolecular forces within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the three-dimensional structure of the compound.
- Analysis of the crystal structure involved identifying bond lengths, bond angles, dihedral angles, and intermolecular interactions.
Main Results:
- The crystal structure of C(11)H(8)FNO was determined, revealing a dihedral angle of 31.93(6)° between aromatic rings.
- Molecules are interconnected by O-H⋯N hydrogen bonds, forming C(9) chains along the c-axis.
- Aromatic pi-pi stacking interactions were observed between pyridine rings with a centroid-centroid separation of 3.7238(16) Å.
Conclusions:
- The crystal packing of C(11)H(8)FNO is governed by a combination of hydrogen bonding and pi-pi stacking interactions.
- These specific intermolecular forces dictate the compound's solid-state architecture and may influence its macroscopic properties.
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