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Updated: May 20, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
2,2'-Sulfonyl-dipyrazine 4-oxide
Ai-Min Li1, Ya Zhang, Zhi-Wei Wang
1Department of Chemistry, Capital Normal University, Beijing 100048, People's Republic of China.
Abstract:
In the title compound, C(8)H(6)N(4)O(3)S, the dihedral angle between the pyrazine rings is 85.04 (1)°. In the crystal, mol-ecules are arranged along the a axis and are linked by C-H⋯N hydrogen bonds and pyrazine-pyrazine π-π inter-actions [centroid-centroid distance = 3.800 (1) Å, forming an infinite chain array. The chains are connected by C-H⋯O(oxide) hydrogen bonds into layers lying parallel to the ab plane. Along the c axis, the layers are stacked and linked through C-H⋯O(sulfon-yl) inter-actions, forming a three-dimensional network.
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