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Updated: May 20, 2026
![Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F51444.jpg&w=3840&q=50)
Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions
Published on: March 20, 2014
1-(2-Chloro-benz-yl)-3,5-dimethyl-2,6-diphenyl-piperidine
Abstract:
Two independent mol-ecules (A and B) comprise the asymmetric unit of the title compound, C(26)H(28)ClN, with the inverted form of B almost superimposable upon A. Each piperidine ring has a chair conformation and the chloro substituent is anti to the piperidine N atom. Each of two aromatic rings, the benzyl residue and one methyl group substituents occupies an equatorial position, and the second methyl substituent occupies an axial position. The dihedral angle formed between the chloro-benzene ring and the flanking phenyl rings in mol-ecule A are 84.24 (9) and 24.85 (8)°; the equivalent angles for mol-ecule B are 79.97 (9) and 28.33 (9)°. In the crystal, the A and B mol-ecules are connected by C-H⋯Cl and C-H⋯π inter-actions, forming a supra-molecular chain along [101].
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