Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...

Stress and Mental Health

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...

The Oral Microbiota

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...

Psychoneuroimmunology: Diabetes and Cancer

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...

Introduction to Stress and Lifestyle

Introduction to Stress and Lifestyle

Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...

Stress Prevention and Stress Management Techniques IV

Stress Prevention and Stress Management Techniques IV

Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The future of periodontal medicine.

Journal of Indian Society of Periodontology·2025

Same author

Fabrication and Characterization of Decellularized Periodontal Ligament Cell Sheet Constructs.

Methods in molecular biology (Clifton, N.J.)·2022

Same author

P4 Medicine as a model for precision periodontal care.

Clinical oral investigations·2022

Same author

Goodbye, Farewell and Amen.

Australian dental journal·2021

Same author

Improving antimicrobial stewardship.

Australian dental journal·2021

Same author

Aged care and artificial intelligence.

Australian dental journal·2021

Same journal

Association between keratinized mucosa width and peri-implant diagnostic parameters in Asian maintenance compliers: A Cross-sectional study.

Journal of the International Academy of Periodontology·2021

Same journal

Periodontal status in cannabis smokers. A systematic review.

Journal of the International Academy of Periodontology·2021

Same journal

Chitosan-based biomaterial and hyaluronic acid on the repair of intrabuccal bone defects in rats.

Journal of the International Academy of Periodontology·2021

Same journal

Immediate implant placement in periodontally infected sites- A systematic review and meta-analysis.

Journal of the International Academy of Periodontology·2021

Same journal

Coefficient of variation of red cell distribution width has correlations to periodontal inflamed surface area in non-obese hypertensive patients.

Journal of the International Academy of Periodontology·2021

Same journal

Impact of Subepithelial Connective Tissue for Root Coverage on Brazilian Patients' Quality of Life: A Longitudinal Clinical Study.

Journal of the International Academy of Periodontology·2021

See all related articles

Search research articles

Related Experiment Video

Updated: May 20, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

How does stress influence periodontitis?

Catherine J Doyle¹, P Mark Bartold

¹Colgate Australian Clinical Dental Research Centre, Department of Dentistry, University of Adelaide.

Journal of the International Academy of Periodontology

|July 18, 2012

Summary

This summary is machine-generated.

Stress significantly contributes to chronic periodontitis, exacerbating periodontal destruction. This review highlights stress as a key factor alongside pathogens in susceptible individuals.

Related Experiment Videos

Last Updated: May 20, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

Area of Science:

Oral health
Immunology
Psychoneuroimmunology

Background:

Stress is a known factor in disease development.
Chronic periodontitis involves destructive inflammatory processes.
The interplay between stress and oral health is increasingly recognized.

Purpose of the Study:

To review the scientific literature on the role of stress in chronic periodontitis.
To evaluate the evidence linking stress to periodontal tissue destruction.

Main Methods:

Literature review of studies investigating stress and periodontitis.
Analysis of evidence for stress as a contributing factor.

Main Results:

Evidence supports stress as a contributing factor in periodontal destruction.
Stress may modulate the host response to periodontal pathogens.

Conclusions:

Stress is a significant factor in the pathogenesis of chronic periodontitis.
Managing stress may be crucial for preventing or mitigating periodontal disease progression.