Related Experiment Video
Updated: May 20, 2026
Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria
Published on: November 10, 2015
[Microsatellite markers and their application in genetic diversity research of Plasmodium spp]
Jun-Wei Li1, Shui-Sen Zhou, Fang Huang
1National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Center for Malaria, Schistosomiasis and Filariasis, Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, China.
Abstract:
Microsatellites, namely simple sequence repeats (SSR), are simple tandemly repeated sequences with repeat units of 1-6 bp in length. As genetic markers, microsatellites are abundant and distributed throughout the eukaryotic genomes. Their advantages include high polymorphism and abundance, co-dominance, selective neutrality and high reliability. In recent years, microsatellite markers are often used to study the biologically genetic diversity. In this paper, we briefly review the application of microsatellite technique in the study of Plasmodium spp. genetic diversity.
