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Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
Published on: October 1, 2007
Electroosmotic flow control in microfluidic chips using a self-assembled monolayer as the insulator of a flow
Li-Chia Chen1, Ching-Chou Wu, Ren-Guei Wu
1Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.
Abstract:
A novel concept for electroosmotic flow (EOF) control in a microfluidic chip is presented by using a self-assembled monolayer as the insulator of a flow field-effect transistor. Bidirectional EOF control with mobility values of 3.4 × 10(-4) and -3.1 × 10(-4) cm(2)/V s can be attained, corresponding to the applied gate voltage at -0.8 and 0.8 V, respectively, without the addition of buffer additives. A relatively high control factor (approximately 400 × 10(-6) cm(2)/V(2) s) can be obtained. The method presented in this study offers a simple strategy to control the EOF.

