Related Experiment Video
Updated: May 20, 2026
Isolation of Murine Intestinal Mesenchyme Resulting in a High Yield of Telocytes
Published on: March 24, 2023
[Location of telocytes in mouse bronchial and pulmonary tissues]
Yong-hua Zheng1, Hua Li, Jun-bo Ge
1Department of Pulmonary, Medicine and Biomedical Research Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Objective:
To explore the location of telocytes in pulmonary tissues.
Methods:
Electron microscopy, immunohistochemistry, primary cell culture and vital cell staining were used to identify the distribution of telocytes in mouse bronchial and pulmonary tissues.
Results:
Telocytes were identified in the interstitial space between bronchial cartilage (cricoid) and smooth muscle by scanning and transmission electron microscope in mouse. By transmission electron micrscope and immunohistochemistry, telocytes were found in the interstitial spaces of lung parenchyma in connection with capillaries and bronchia. Telocytes expressed CD34, c-kit and vimetin by immunohistochemistry. After isolation, cultured telocytes demonstrated typical morphological feature, i.e. cells with telopode, which was seen as luminal structures with alternating thin and thick segments under electron microscope.
Conclusion:
Telocytes are present in the interstitial space between cricoid cartilage and smooth muscle.
Related Concept Videos
01:26Alveoli and Alveolar Ducts
01:23The Bronchial Tree
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...